tag:blogger.com,1999:blog-60489180681746456882024-03-20T22:30:57.482-07:00Microextraction TechThis blog is devoted to the use of microextraction techniques in Analytical ChemistryUnknownnoreply@blogger.comBlogger123125tag:blogger.com,1999:blog-6048918068174645688.post-80156366902924424222022-05-25T10:20:00.002-07:002022-05-25T10:20:30.666-07:00Pre‑cleaned bare wooden toothpicks for the determination of drugs in oral fluid by mass spectrometry
Our latest article, published as a paper in the forefront in Analytical and Bioanalytical Chemistry, presents a deep study of the reduction of the intrinsic components of wooden toothpicks (WTs) towards their use as a sorptive phase in the determination of six tricyclic antidepressants (amitriptyline, clomipramine, desipramine, imipramine, nortriptyline, and trimipramine) in saliva by direct Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-6048918068174645688.post-50137459833296020322021-02-02T08:25:00.000-08:002021-02-02T08:25:35.512-08:00Effervescence-Assisted Microextraction: One Decade of Developments A decade ago, our research group introduced the
concept of effervescence-assisted microextraction. The first approach of this
alternative consisted of a micrometric sorbent (OASIS-HLB) compressed in a
tablet along with a carbon dioxide source (sodium carbonate) and a proton donor
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research, wooden toothpicks (WTs) coated with a commercial polyamide such as
nylon-6 (N6) were used in a solid phase microextraction (SPME) procedure for
the determination of methadone, cocaine, and methamphetamine in saliva. Bare WTs
present weak hydrophilic and hydrophobic forces provided by cellulose and
lignocellulose, respectively. Consequently, the N6 polymeric coating Unknownnoreply@blogger.com0Córdoba, Spain37.8881751 -4.77938359.5779412638211525 -39.9356335 66.198408936178851 30.3768665tag:blogger.com,1999:blog-6048918068174645688.post-39883495865503192872020-04-08T02:50:00.000-07:002020-04-08T02:57:40.656-07:00Paper coated with silver nanoflower composite, a dual substrate for SERS and PS-MS
Recently a novel dual substrate for both
SERS and PS-MS based on the deposition of silver nanoflowers (AgNFs) onto a
paper-based analytical device (PAD) has been developed. Although the obtention
of the substrate requires several steps, it is possible to synthesize a bunch
of them at the same time. Figure 1 illustrates the different stages involved in
the synthesis process of the so-called Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-6048918068174645688.post-83707506417197663992018-03-12T00:26:00.000-07:002019-11-16T00:46:46.768-08:00Polyacrylamide gel in electromembrane extraction<!--[if gte mso 9]>
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Microextraction Techhttp://www.blogger.com/profile/10023489894901848049noreply@blogger.com0tag:blogger.com,1999:blog-6048918068174645688.post-9846688469560596942017-06-15T03:19:00.001-07:002019-11-16T00:21:32.612-08:00Dendrimeric nanocomposites for solid phase microextraction
Polymeric nanocomposites have demonstrated great potential as sorbents in analytical sample preparation. The polymeric domain usually provides the sorption ability while the nanometric element confers special properties (like magnetism) or improves the sorptive capacity introducing new interaction chemistries (different than those provided by the polymer) or increasing the superficial area of Microextraction Techhttp://www.blogger.com/profile/10023489894901848049noreply@blogger.com0tag:blogger.com,1999:blog-6048918068174645688.post-18812272367723055452017-05-20T01:13:00.003-07:002017-05-20T01:13:31.855-07:00Polysulfone and MIPs coated over nickel foam
Microextraction is currently present in many analytical
processes. Its advantages over conventional extraction approaches have been
extensively pointed out and mainly refer to its simplicity and miniaturization
while providing equal or even better analytical features. Also, the
availability of the sorbents (carbon-based, silica, metallic, magnetic...), formats (fiber, capillary, powder, Microextraction Techhttp://www.blogger.com/profile/10023489894901848049noreply@blogger.com0tag:blogger.com,1999:blog-6048918068174645688.post-64854057780036195752017-04-03T01:15:00.003-07:002017-04-03T02:37:53.581-07:00Animal bones wastes for coiled solid phase microextraction
The use of natural products, or wastes from them, to fabricate sorptive
phases is an interesting research line with green connotations. Ramzi and
Farrokhzadeh have evaluated, in a recent article accepted for publication in
Journal of Separations Science, the potential use of animal bone wastes in this
context. From the chemical point of view, bones are inorganic/organic composite
materials whereMicroextraction Techhttp://www.blogger.com/profile/10023489894901848049noreply@blogger.com0tag:blogger.com,1999:blog-6048918068174645688.post-69391051962515446702017-03-02T06:37:00.000-08:002017-03-02T06:37:28.703-08:00Direct coupling of Solid Phase Microextraction to Mass Spectrometry: via liquid desorption
The direct coupling of SPME
with Mass Spectrometry (MS) analyzers has been investigated for more than 20
years. In fact, different strategies have been developed by several groups worldwide
and most have been appropriately reviewed by Fang et al<!--[if supportFields]>ADDIN CSL_CITATION {
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"itemData" : { "DOI"Microextraction Techhttp://www.blogger.com/profile/10023489894901848049noreply@blogger.com0tag:blogger.com,1999:blog-6048918068174645688.post-70289527682629062232016-11-09T03:49:00.000-08:002016-11-09T03:49:07.471-08:00MNPs-Nylon 6 composite as a new sorbent for microextraction
In 2014 a new method for the synthesis of magnetic nanoparticles (MNPs)-nylon
6 composite was proposed. This method is simple and quick since only one step
is needed. It is based on a solvent changeover, taking advantage of the
different solubility of nylon 6 in formic acid and water. In Figure 1, it can
be observed how this synthesis is carried out. The solution of MNPs and nylon-6
in formic Microextraction Techhttp://www.blogger.com/profile/10023489894901848049noreply@blogger.com0tag:blogger.com,1999:blog-6048918068174645688.post-70385844052390828712016-11-07T07:12:00.003-08:002016-11-07T07:12:31.977-08:00ICE concentration for improving stir bar sorptive extraction
Freeze concentration (FC) is a separation technique
scarcely exploited for sample treatment in Analytical Chemistry although it has
been successfully applied in the industrial field. For example, FC is used in
the food industry to extract water avoiding losses of (semi)volatile and
thermolabile compounds producing extracts enriched in the solutes of interest.
FC is based on the fact that Microextraction Techhttp://www.blogger.com/profile/10023489894901848049noreply@blogger.com0tag:blogger.com,1999:blog-6048918068174645688.post-17551030764776785702016-11-01T02:03:00.000-07:002016-11-01T02:03:14.315-07:00Read all posts from October 2016
Optical monitoring of single drop microextraction
Single drop microextraction, the first liquid phase
microextraction technique, is a simple approach consisting of the extraction of
the target analytes from the sample into a small drop of extractant. The
characteristics of the drop, specially its chemical nature and mechanical
stability, are key to guarantee the success of the extraction. The Microextraction Techhttp://www.blogger.com/profile/10023489894901848049noreply@blogger.com0tag:blogger.com,1999:blog-6048918068174645688.post-46554569931494767852016-10-26T14:09:00.000-07:002016-10-26T14:09:06.074-07:00Trapping analytes with carbon nanotubes sponges
Carbon nanotubes sponges are three dimensional
structures formed by the random self-assembly of these nanostructures during
their synthesis. They are produced by the classical chemical vapor deposition
method simply using special catalysts like ferrocene. The structure of an
sponge can be observed in Figure 1A which shows a scanning electron micrograph
of the bulk material. A closer view (FigureMicroextraction Techhttp://www.blogger.com/profile/10023489894901848049noreply@blogger.com0tag:blogger.com,1999:blog-6048918068174645688.post-78570362712257612252016-10-18T23:15:00.001-07:002016-10-18T23:17:12.093-07:00Moving miniaturization a step forward
Microextraction techniques have evolved from classical extraction procedures following three main trends,
namely: miniaturization, simplification and automation, which have not received
a similar attention in the last decades. In fact, simplification and
miniaturization (in different degrees) are almost inherent to the majority of
the new approaches while automation is, in some cases, consideredMicroextraction Techhttp://www.blogger.com/profile/10023489894901848049noreply@blogger.com0tag:blogger.com,1999:blog-6048918068174645688.post-78736893079349999692016-10-14T09:24:00.001-07:002016-10-14T09:26:25.198-07:00Optical monitoring of single drop microextraction
Single drop microextraction (SDME), the first liquid phase
microextraction technique proposed, is a simple approach consisting of the extraction of
the target analytes from the sample into a small drop of extractant. The
characteristics of the drop, specially its chemical nature and mechanical
stability, are key factors to guarantee the success of the extraction. Its chemical
composition definesMicroextraction Techhttp://www.blogger.com/profile/10023489894901848049noreply@blogger.com2tag:blogger.com,1999:blog-6048918068174645688.post-19993255333130639862016-06-24T03:13:00.000-07:002016-06-24T03:13:31.505-07:00Fully automated electromembrane extraction
The implementation of microextraction techniques in
process laboratories usually depends on their automation degree. In reality,
the use of too manual procedures is not practical when a large number of
samples must be processed. In addition, manual workflows are labor intensive and prone to errors. This situation can be further complicated when risky
samples, pretty common in bioanalysis, are Microextraction Techhttp://www.blogger.com/profile/10023489894901848049noreply@blogger.com1tag:blogger.com,1999:blog-6048918068174645688.post-66475340602920735002016-06-15T04:25:00.001-07:002016-06-15T04:25:50.577-07:00Cost effective imprinting for purification purposes
Selectivity is a main issue in any analytical process.
Many strategies can be proposed to achieve the highest value of this basic
analytical property. Among them, the use of selective sorbents can be highlighted.
There are several alternatives that can be used to synthesize them, being the
molecular imprinting one of the most reported. The so-called molecularly
imprinted polymers (MIP) are Microextraction Techhttp://www.blogger.com/profile/10023489894901848049noreply@blogger.com0tag:blogger.com,1999:blog-6048918068174645688.post-37724831347050785142016-06-10T11:03:00.001-07:002016-06-10T11:03:50.787-07:00Thin electrospun films based extraction directly coupled with mass spectrometry
Electrospun fibres (EFs) have a great potential in
microextraction techniques thanks to their advantageous characteristics. They
are versatile as a relatively large number of different polymers, with different
interaction chemistries, can be used as precursors. In addition, the
use of mixtures of polymers as well as the introduction of nanoparticles in the
fibrous network have extended the Microextraction Techhttp://www.blogger.com/profile/10023489894901848049noreply@blogger.com0tag:blogger.com,1999:blog-6048918068174645688.post-49472508742017621372016-06-01T02:28:00.000-07:002016-06-01T02:28:03.429-07:00Solid-liquid extraction in hard cap espresso machine
Despite the importance of solid-liquid extraction in
the analysis of solid materials, this technique has been scarcely discussed in
this blog. This post aims to be an inflection point in this trend and we have
selected a very interesting article for this purpose. The article has been
published in Analytical Chemistry by our colleagues from Valencia (Spain) under
the appealing title "Hard cap Microextraction Techhttp://www.blogger.com/profile/10023489894901848049noreply@blogger.com0tag:blogger.com,1999:blog-6048918068174645688.post-69420729448936079892016-05-20T09:03:00.000-07:002016-05-20T09:03:03.299-07:00Droplet microextraction for single cell mass spectrometric analysis
Miniaturization of classical extraction procedures,
which was the origin of microextraction techniques, has reduced the
consumption/requirement of extractant solvents in the liquid-based formats from
the mL to the mL
range. The use of lower droplets, at the nL or even pL levels, opens a door to
process special systems characterized by their small sizes or low availability.
In a previous post, weMicroextraction Techhttp://www.blogger.com/profile/10023489894901848049noreply@blogger.com0tag:blogger.com,1999:blog-6048918068174645688.post-10245759912371684462016-01-16T11:00:00.000-08:002016-01-16T11:00:24.583-08:00Graphene membranes for microextraction
Carbon nanoparticles and specifically carbon nanotubes
can be considered as an inflection point in the development of microextraction
techniques on account of their excellent sorbent properties. This fact permits
the reduction of the dimensions of the extraction step while maintaining or even
improving the preconcentration of the target compounds on the nanosorbent. Since
then, different Microextraction Techhttp://www.blogger.com/profile/10023489894901848049noreply@blogger.com1tag:blogger.com,1999:blog-6048918068174645688.post-19893812798706249722016-01-03T05:06:00.001-08:002016-01-03T05:06:36.119-08:00Our three most-read blog posts of 2015
The study of historical documents: morphine in
Bulgakov´s famous manuscript
Mikhail Bulgakov was a recognized writer
born in Kiev in 1891. His famous novel, The master and Margarita, criticizes
the soviet society and the literature establishment. He wrote the novel by the
end of his life. In these days, Bulgakov was suffering nephrosis that caused
his death in 1940.(read more)
Magnetic Microextraction Techhttp://www.blogger.com/profile/10023489894901848049noreply@blogger.com0tag:blogger.com,1999:blog-6048918068174645688.post-18102997067822425922016-01-01T02:54:00.000-08:002016-01-01T02:54:39.542-08:00Read all posts from December 2015
Magnetic SPME in micro-fluidics, speciation of Hg in
cells
Mercury is a well known toxicant with
different exposure sources. Although its use on medical products is banned in
many countries, other sources like environmental pollution or contaminated food
still exist. Professor Bin Hu and co-workers have been recently researched how
Hg species are distributed and even modified in cell cultures [Microextraction Techhttp://www.blogger.com/profile/10023489894901848049noreply@blogger.com0tag:blogger.com,1999:blog-6048918068174645688.post-44439845006948526642015-12-14T05:42:00.000-08:002015-12-14T05:42:20.718-08:00Laser desorption combined with SPME for GC-MS analyses
We highlight today an article that describes the
combination of laser desorption and solid phase microextraction (SPME) for the
analysis of solid samples. The article has been published in Rapid
Communications in Mass Spectrometry under the title "Laser desorption sample transfer for gas chromatography/mass
spectrometry" (1). It is not
necessary to describe the potential of SPME since it is a Microextraction Techhttp://www.blogger.com/profile/10023489894901848049noreply@blogger.com2tag:blogger.com,1999:blog-6048918068174645688.post-71900848648149606932015-12-10T08:17:00.000-08:002015-12-10T08:17:11.025-08:00Rapid extraction of nucleic acids for quick diagnosis
Nucleic acids have several practical applications in Analytical Sciences as they can be used
as biorecognition molecules (e.g. aptamer) in the design of sensors and even
extraction phases. However, this post deals with those methods that are aimed
to determining nucleic acids in samples of different origin (usually
biosamples). Among these applications, we can highlight paternity tests, the
Microextraction Techhttp://www.blogger.com/profile/10023489894901848049noreply@blogger.com0